I am a Medicinal Chemist with corporate and consulting experience in biotechnology. I was also a faculty member in a Chemistry department at a small university. I have begun to study Japanese because I am impressed by Japan's strength in science and engineering.
Genzyme (Sanofi Genzyme)
从 20210719 12:00 上午
Developed unique purification process for extracting acid alpha-glucosidase from cell culture broth
Optimized production conditions for Cerezyme; recombinant protein therapy for Gaucher’s disease with HPLC, low pressure chromatography, UV/VIS spectrometry, IEF and SDS PAGE analysis as analytical techniques
Assistant Professor of Chemistry
美国, Huntsville Alabama
从 20130801 12:00 上午 直到 20210106 12:00 上午
I taught undergraduate chemistry courses and guided students in undergraduate research.
The University of Iowa
PhD in Medicinal and Natural Products Chemistry
美国, Iowa City
从 20040801 12:00 上午 直到 20091031 12:00 上午
Ph.D. Thesis: “Glycan Targeted Gene Delivery to the Dendritic Cell SIGN Receptor”
My research project centered around the development of a novel targeting ligand for non-viral gene delivery. The ligand I prepared contains a high-mannose N-glycan obtained through affinity purification and enzymatic digestion of a natural glycoprotein. The project required the synthesis of an unnatural amino acid used in solid phase peptide synthesis. The N-glycan was conjugated to a unique synthetic peptide, and the resulting glycopeptide vehicle was used to establish receptor mediated gene delivery in cell culture. I showed that the glycopeptide vehicle produced selective gene transfer by targeting the DC-SIGN receptor.